It is done in three sessions at four to six week intervals. Collagen builds over two to three months, which is how long the skin takes to make it as the powder dissolves. Keeping the interval lets each session’s response settle before the next accumulates.

It does not fill immediately but appears gradually over two to three months, because the powder does not create volume itself — it prompts the skin to make collagen at that spot as it dissolves. Looking puffy right after comes from the liquid it is mixed with and subsides within days.

Both are collagen-stimulating injectables and differ in material. Sculptra uses the material found in absorbable sutures; Ultracol uses the material found in dissolving lifting threads, milled to a fine powder. Ultracol comes at 200 mg per vial, with a finer-particle 100 mg product also available.